English Version

【讲座预告】Engineering Biomolecules for Biomedical Imaging and Drug Delivery

时间:2016-10-17 阅读次数:


报告人:Zheng-Rong Lu 教授

(Case Western Reserve University, Cleveland, Ohio)

时间:10月18日(周二) 10:00



Biomolecular engineering bridges the gap between basic research and clinical needs. We have designed and developed polydisulfide-based biodegradable macromolecular MRI contrast agents for evaluating tumor angiogenesis and targeted Gd(III) based MRI contrast agents for detecting a cancer-related biomarker expressed in the extracellular matrix of malignant tumors. We have also developed simple and smart multifunctional delivery systems to deliver therapeutic siRNAs into the cytoplasm of cancer cells to regulate the expression of disease related genes to effectively treat life-threatening diseases, including metastatic and drug resistance breast cancer.


Dr. Zheng-Rong Lu is M. Frank Rudy and Margaret Domiter Rudy Professor of Biomedical Engineering at the Department of Biomedical Engineering, Case School of Engineering, Case Western Reserve University. Dr. Lu’s research efforts involve molecular imaging, novel MRI contrast agents, image-guided photodynamic therapy, polymeric drug delivery systems and multifunctional delivery systems for nucleic acids.He serves on the scientific advisory board of Pharmaceutical Research, Molecular Pharmaceutics and the American Journal of Nuclear Medicine and Molecular Imaging. 

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